EFFICACY OF ADDITIONAL USE OF HYALURONIC ACID GEL ON HARD AND SOFT TISSUE CHANGES AROUND DENTAL IMPLANTS: AN IN VIVO STUDY
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- mesial and distal crestal bone level
研究概览
简要总结
This study will be conducted and compiled by Dr. Mayank Gupta, Dr. Manish Khatri, Dr. Mansi Bansal, Dr. Vimal Kumar and Dr. Pratiksha Tripathi at Department Of Periodontology, Institute of Dental Studies and Technologies, Modinagar, Uttar Pradesh, India. The study is a randomized control trial for evaluation of efficacy of Hyaluronic acid gel on implants. Hyaluronic acid is used as a coating, acts on migration, adhesion, proliferation and differentiation of cellular precursors on titanium implants improving the connection between implant and bone. Assessment and comparison of various parameters like bone density, crestal heights, probing depth around implants will be done.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with good oral hygiene will be included if they are systemically healthy and have minimum two or even multiple number of missing teeth with adequate inter-occlusal clearance (distance between opposing teeth and edentulous space).
排除标准
- •Patients will be excluded if they are smokers or have para-functional habits, uncontrolled diabetes, blood disorders, immune-compromised state, acute infection at site or aggressive periodontal disease.
- •Patients on bisphosphonates, pregnant and lactating women will also be excluded from the study.
结局指标
主要结局
mesial and distal crestal bone level
时间窗: For bone density and mesial and distal crestal bone level at baseline(immediately after implant placement), 1 month, 3 months and 6 months | Probing depths at baseline(just after prosthesis placement), 1 month and 3 months after prosthesis placement
bone density
时间窗: For bone density and mesial and distal crestal bone level at baseline(immediately after implant placement), 1 month, 3 months and 6 months | Probing depths at baseline(just after prosthesis placement), 1 month and 3 months after prosthesis placement
Probing depths at four sites
时间窗: For bone density and mesial and distal crestal bone level at baseline(immediately after implant placement), 1 month, 3 months and 6 months | Probing depths at baseline(just after prosthesis placement), 1 month and 3 months after prosthesis placement
次要结局
- Modified Plaque index(Simplified Gingival Index)