Comparison of two treatments for improving the outcomes in awake intubatio
Phase 2
- Conditions
- Failed or difficult intubation.Failed or difficult intubation
- Registration Number
- IRCT20161220031487N9
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
Age range 20 to 60 years
ASA grade 1-2
Candidate for elective surgical operation in Rasoule-Akram hospital
Candidate for awake intubation
Exclusion Criteria
Pregnant women
Patients not able to collaborate (intellectual disability, low awareness, ...)
Patients with A-V block in ECG
Patients addicted to drugs of abuse or analgesics
History of allergic reaction to each of the drugs under study
Emergency operation
Heart failure
Uncontrolled asthma
Incidence of adverse effects during study (including laryngospasms, bronchospasm, Ramsey scale >4 , any kind of hemodynamic changes requiring pharmaceutical intervention)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Heart rate. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Using patient monitoring system.;Blood pressure. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Using patient monitoring system.;Arterial blood gas analysis. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Arterial blood gas analysis system.;Analgesia. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Ramsey sedation scale.
- Secondary Outcome Measures
Name Time Method Attempts for awake intubation with fiber optic. Timepoint: During intubation. Method of measurement: Counting the number of attempts for intubation.