CTRI/2024/09/073494尚未招募不适用
Metabolomics Evaluation in Patients Post Renal Transplantation
未提供1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2024年10月15日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Change in urine metabolite levels pre and post transplant
研究概览
简要总结
This study aims to investigate the potential of urine metabolomics as a non-invasive tool to predict renal transplant outcomes. Patients undergoing renal transplantation will be recruited from the nephrology department of Kasturba Medical College Hospital. Baseline urine samples will be collected one month prior to transplantation, followed by additional samples at three months post-transplant. A metabolomic analysis will be performed on these samples using the GC/MS method to identify potential biomarkers associated with graft function and patient outcomes. T
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients above the age of 18 diagnosed with CKD are approved to receive kidney transplants and are willing to participate.
排除标准
- •Patients not receiving transplant at Kasturba Hospital.
结局指标
主要结局
Change in urine metabolite levels pre and post transplant
时间窗: 4 months
次要结局
- Change in urine metabolite levels in pre transplant and Acute Tubular Necrosis(4 months)
- Change in urine metabolite levels in pre transplant and Transplant Rejection(4 months)
研究者
Dr Mohan V Bhojaraja
Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal
研究点 (1)
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