Evaluation of a chlorhexidine mouthwash for the eradication of asymptomatic pharyngeal Neisseria gonorrhoeae infection - MoNg study

Institute of Tropical Medicine0 个研究点目标入组 100 人开始时间: 2019年12月5日最近更新: 2022年8月8日

适应症

试验速览

暂无简介。

•1. Able and willing to provide written informed consent
•2. Male sex at birth
•3. At least 18 years old
•4. Having had sex with another man within the previous 12 months
•5. Confirmed diagnosis of asymptomatic pharyngeal NG infection as defined by no symptoms of pharyngitis and no signs of disseminated gonococcal disease plus test positive for NG on NAAT or culture within the previous 14 days.
•6. Willing to abstain from any sexual intercourse until the result of the final test-of-cure is reported to be negative
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 90
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 10

•1. Known contra-indication or allergy to chlorhexidine
•2. Proven gonococcal infection elsewhere, signs of disseminated gonococcal disease or proven or suspected coinfection with Chlamydia trachomatis (CT) or syphilis at the time of the screening visit.
•3. Currently using a mouthwash and unwilling to stop using it for the duration of the study or being included in another research project using mouthwashes
•4. Currently taking any antibiotics or having taken any antibiotics in the previous 14 days

发起方

Institute of Tropical Medicine