Hydrogen Inhalation for Health and Exercise Performance
- Conditions
- Exercise Performance
- Registration Number
- NCT03846141
- Lead Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
- Brief Summary
In this randomized double-blind, placebo-controlled, crossover pilot trial, we evaluated the effects of 7-day H2 inhalation on exercise performance outcomes and serum hormonal and inflammation profiles in a cohort of young men and women.
- Detailed Description
All participants were allocated to receive either gaseous hydrogen (4%) or placebo (room air) by 20-min once-per-day inhalation for 7 days, with wash-out period of 7 days to prevent the residual effects of interventions across study periods. The primary treatment outcome was the change in running time-to-exhaustion from baseline to day 7. Additionally, assessment of other exercise performance endpoints and clinical chemistry biomarkers were performed at baseline and after 7 days after each intervention.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Age ≥ 18 -35 years Body mass index 20 - 25 kg/m2 Free of major diseases Physically active Must be able to give written informed consent
Use of any dietary supplements within 4 weeks before study commences Abnormal values for lab clinical chemistry (> 2 SD)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Change in exercise performance Change from baseline running time-to-exhaustion at 7 days Running time-to-exhaustion
- Secondary Outcome Measures
Name Time Method Change in exercise performance Change from baseline maximal voluntary isometric strength at 7 days Maximal voluntary isometric strength
Change in clinical chemistry biomarker Change from baseline serum ghrelin at 7 days Ghrelin
Trial Locations
- Locations (1)
FSPE Applied Bioenergetics Lab
🇷🇸Novi Sad, Vojvodina, Serbia
FSPE Applied Bioenergetics Lab🇷🇸Novi Sad, Vojvodina, Serbia