Hydrogen Inhalation for Health and Exercise Performance
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Exercise Performance
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Change in exercise performance
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
In this randomized double-blind, placebo-controlled, crossover pilot trial, we evaluated the effects of 7-day H2 inhalation on exercise performance outcomes and serum hormonal and inflammation profiles in a cohort of young men and women.
Detailed Description
All participants were allocated to receive either gaseous hydrogen (4%) or placebo (room air) by 20-min once-per-day inhalation for 7 days, with wash-out period of 7 days to prevent the residual effects of interventions across study periods. The primary treatment outcome was the change in running time-to-exhaustion from baseline to day 7. Additionally, assessment of other exercise performance endpoints and clinical chemistry biomarkers were performed at baseline and after 7 days after each intervention.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age ≥ 18 -35 years Body mass index 20 - 25 kg/m2 Free of major diseases Physically active Must be able to give written informed consent
Exclusion Criteria
- •Use of any dietary supplements within 4 weeks before study commences Abnormal values for lab clinical chemistry (\> 2 SD)
Outcomes
Primary Outcomes
Change in exercise performance
Time Frame: Change from baseline running time-to-exhaustion at 7 days
Running time-to-exhaustion
Secondary Outcomes
- Change in exercise performance(Change from baseline maximal voluntary isometric strength at 7 days)
- Change in clinical chemistry biomarker(Change from baseline serum ghrelin at 7 days)