Hydrogen Inhalation for Health and Exercise Performance
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Change in exercise performance
研究概览
简要总结
In this randomized double-blind, placebo-controlled, crossover pilot trial, we evaluated the effects of 7-day H2 inhalation on exercise performance outcomes and serum hormonal and inflammation profiles in a cohort of young men and women.
详细描述
All participants were allocated to receive either gaseous hydrogen (4%) or placebo (room air) by 20-min once-per-day inhalation for 7 days, with wash-out period of 7 days to prevent the residual effects of interventions across study periods. The primary treatment outcome was the change in running time-to-exhaustion from baseline to day 7. Additionally, assessment of other exercise performance endpoints and clinical chemistry biomarkers were performed at baseline and after 7 days after each intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 18 -35 years Body mass index 20 - 25 kg/m2 Free of major diseases Physically active Must be able to give written informed consent
排除标准
- •Use of any dietary supplements within 4 weeks before study commences Abnormal values for lab clinical chemistry (> 2 SD)
研究组 & 干预措施
Placebo
Room air for inhalation
干预措施: Placebo (Other)
Hydrogen
Hydrogen (4%) for inhalation
干预措施: Hydrogen (Other)
结局指标
主要结局
Change in exercise performance
时间窗: Change from baseline running time-to-exhaustion at 7 days
Running time-to-exhaustion
次要结局
- Change in exercise performance(Change from baseline maximal voluntary isometric strength at 7 days)
- Change in clinical chemistry biomarker(Change from baseline serum ghrelin at 7 days)