Evaluation of Regression of New Vessel Formation in Retina in case of Proliferative Diabetic Retinopathy after Laser v/s after Intra Vitreal Anti VEGF injection using Retinal Angiography Imaging Technique
Not Applicable
- Conditions
- Health Condition 1: - Health Condition 2: O- Medical and SurgicalHealth Condition 3: O- Medical and Surgical
- Registration Number
- CTRI/2023/05/052391
- Lead Sponsor
- SANKARA EYE HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients with Treatment naïve proliferative diabetic retinopathy (NVE/NVD)
2.Willing to undergo PRP/Anti VEGF injections
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Exclusion Criteria
1.Other causes of neovascularisation (Retinal vein occlusion, fibrovascular proliferation with retinal traction, fibrosis, scarring, atrophy)
2.Diabetic Macular Edema
3.Vitreous hemorrhage which obscures imaging
4.Uncontrolled glaucoma
5.Outside OCTA scan range
6.Previous history of optic neuropathy
7.Poor quality scans(media opacity)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in area of neovascularization on OCT AngiographyTimepoint: 1. PRP group: Baseline,at 1st PRP, at 1 week, at 2 weeks, at 3 weeks, at 1 month and at 3 months <br/ ><br> <br/ ><br>2. Anti VEGF group: Baseline, at 1st injection, at 1 month, at 2 months, at 3 months
- Secondary Outcome Measures
Name Time Method Observation of complications related to therapy <br/ ><br>Timepoint: 1. PRP group: 1 week post PRP,2 weeks post PRP, 3 weeks post PRP, at 1 month and at 3 months <br/ ><br> <br/ ><br>2. Anti VEGF Group: post injection at 1 month, at 2 months and at 3 months