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Clinical Trials/IRCT20090808002306N7
IRCT20090808002306N7
Recruiting
Phase 2

The effectiveness of oral N-acetylcysteine (NAC) comparing to placebo on quality of life and respiratory profile of patients aged 6 to 18 years old with cystic fibrosis having mild to moderate pulmonary involvement

Esfahan University of Medical Sciences0 sites45 target enrollmentTBD
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Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Not specified
Sponsor
Esfahan University of Medical Sciences
Enrollment
45
Status
Recruiting
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\. The amount of chlorine in the sweat test is greater than or equal to 60 milliequivalents per liter or the presence of genotype containing two diagnostic mutations associated with CF and accompanied by one or more stable clinical symptoms specific to the specific phenotype of cystic fibrosis patients.
  • •2\. patients aged range of 6 to 18 years
  • •3\. The level of FEV1 or Forced Expiratory Volume is more than 50%
  • •4\. Stable clinical condition in the patient and no acute infection in the patient's upper and lower respiratory system
  • •5\. Do not aggravate the patient's pulmonary symptoms for 14 days before the patient's clinical examination

Exclusion Criteria

  • •Disability to perform and repeat spirometry test according to American Thoracic Society criteria
  • •use of other drugs out of the common treatment protocol that is effective on the disease.
  • •Having possible history of underlying cardiovascular, renal, hepatic and biliary tract diseases

Outcomes

Primary Outcomes

Not specified

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