The incidence of pulmonary embolism in patients undergoing abdominal flap breast reconstructions, a prospective study.

Not yet recruiting

• Conditions: bloodclot in the lungs; thrombus in the lungs; 10006232; 10006295; 10014523

• Registration Number: NL-OMON41914
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 422

Inclusion Criteria

All patients undergoing an abdominal flap breast reconstruction.
Aged 18 years or older

Exclusion Criteria

Inability to confirm to the thrombosis prophylaxis protocol.
Patients who are on anticoagulant medication or have coagulopathy.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The occurrence of a pulmonary embolism.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>To asses potential risk factors on pulmonary embolism: age, body mass index,<br /><br>BRCA1 and BRCA2 gene mutations, smoking, a history of cancer, presence of<br /><br>malignancy at the time of reconstruction, chemotherapy or hormonal therapy at<br /><br>the time of reconstruction, previous radiotherapy, timing of reconstruction<br /><br>(primary or secondary), laterality of reconstruction (unilateral or bilateral),<br /><br>operation duration, complication other than pulmonary embolism and number of<br /><br>re-operations will be recorded.<br /><br>To investigate the potential etiology of pulmonary embolism in patients<br /><br>undergoing an abdominal based breast reconstruction.</p><br>