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Clinical Trials/NCT04952363
NCT04952363
Completed
Not Applicable

The Effect of Whole Body Vibration Training on Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease

Kaohsiung Medical University Chung-Ho Memorial Hospital1 site in 1 country26 target enrollmentDecember 22, 2017
ConditionsCOPD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
COPD
Sponsor
Kaohsiung Medical University Chung-Ho Memorial Hospital
Enrollment
26
Locations
1
Primary Endpoint
chronic obstructive pulmonary disease assessment test (CAT)
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Although whole body vibration (WBV) is mainly designed to promote neuromuscular function, however, because of its vibration characteristics, whether it can provide additional effects on the sputum clearance for chronic obstructive pulmonary (COPD) disease patients, thereby improving the quality of life, and exercise capacity is still unknown.

Registry
clinicaltrials.gov
Start Date
December 22, 2017
End Date
November 1, 2018
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Confirmed diagnosis of COPD at the outpatient thoracic medicine clinic
  • Need HFCWO as judged by the doctor

Exclusion Criteria

  • Acute COPD exacerbation within the previous 4 weeks,
  • Contraindication for WBVT (e.g., artificial joint replacement, a history of deep vein thrombosis, or known aortic aneurysm)
  • Inability to perform squatting exercises
  • Acute disc disease
  • Inability to complete the 6MWT

Outcomes

Primary Outcomes

chronic obstructive pulmonary disease assessment test (CAT)

Time Frame: 8 weeks

questionnaire of COPD symptoms, scores ranging from 0 to 40, higher scores indicating more severe impact of COPD on their life

FVC(% pred)

Time Frame: 8 weeks

percentage of predicted FVC value (% pred)

1 min STST

Time Frame: 8 weeks

the number of repetitions performed in the 1-min sit-to-stand test (rep.)

FVC

Time Frame: 8 weeks

forced vital capacity tested in pulmonary function test (Liters)

Distance-Saturation Product (DSP)

Time Frame: 8 weeks

the product of distance walked and lowest oxygen saturation during the 6-min walk test (m%)

FEV1/FVC

Time Frame: 8 weeks

forced expiratory volume in 1 second divided by forced vital capacity in pulmonary function test (%)

Predicted distance

Time Frame: 8 weeks

percentage of the predicted 6 minute walk test distance (%pred)

5-rep STST

Time Frame: 8 weeks

the complete time for the 5-repetition sit-to-stand test (sec)

Muscle strength test2

Time Frame: 8 weeks

maximal force output for quadriceps muscle (lbs)

X-ray score

Time Frame: 8 weeks

the evaluation of the chest radiography based on the sputum impaction score, scores ranging from 0 to 18. A decrease in score represented an improvement in sputum in each area.

modified Medical Research Council (mMRC)

Time Frame: 8 weeks

questionnaire of dyspnea, scores ranging from 0 (low degree of dyspnea) to 4 (high degree of dyspnea)

Saint George Respiratory Questionnaire (SGRQ)

Time Frame: 8 weeks

questionnaire of overall health, daily life, and perceived well-being, scores ranging from 0 (no health impairment) to 100 (maximum health impairment)

FEV1

Time Frame: 8 weeks

forced expiratory volume in 1 second in pulmonary function test (Liters)

FEV1(% pred)

Time Frame: 8 weeks

percentage of predicted FEV1 value (% pred)

6 min walk distance

Time Frame: 8 weeks

the distance walked in 6 minutes (m)

Muscle strength test1

Time Frame: 8 weeks

Maximal force output for biceps femoris muscle (lbs)

Sputum self-assessment scale

Time Frame: 8 weeks

questionnaire of sputum volume, it contained three items (0-25 mL/d, 25-50 mL/d, and 50-100 mL/d) as a checklist

Study Sites (1)

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