The Effect of Whole Body Vibration Training on Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 26
- Locations
- 1
- Primary Endpoint
- FVC(% pred)
Study Overview
Brief Summary
Although whole body vibration (WBV) is mainly designed to promote neuromuscular function, however, because of its vibration characteristics, whether it can provide additional effects on the sputum clearance for chronic obstructive pulmonary (COPD) disease patients, thereby improving the quality of life, and exercise capacity is still unknown.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 35 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Confirmed diagnosis of COPD at the outpatient thoracic medicine clinic
- •Need HFCWO as judged by the doctor
Exclusion Criteria
- •Acute COPD exacerbation within the previous 4 weeks,
- •Contraindication for WBVT (e.g., artificial joint replacement, a history of deep vein thrombosis, or known aortic aneurysm)
- •Inability to perform squatting exercises
- •Acute disc disease
- •Inability to complete the 6MWT
Arms & Interventions
HFCWO+WBVT
Subjects received HFCWO+WBVT intervention twice a week for a period of 8 weeks
Intervention: A vertical vibration platform PowerVibe Zen Pro 5900 (Device)
HFCWO+WBVT
Subjects received HFCWO+WBVT intervention twice a week for a period of 8 weeks
Intervention: HFCWO (Device)
HFCWO only
Subjects received HFCWO intervention twice a week for a period of 8 weeks
Intervention: HFCWO (Device)
Outcomes
Primary Outcomes
FVC(% pred)
Time Frame: 8 weeks
percentage of predicted FVC value (% pred)
chronic obstructive pulmonary disease assessment test (CAT)
Time Frame: 8 weeks
questionnaire of COPD symptoms, scores ranging from 0 to 40, higher scores indicating more severe impact of COPD on their life
1 min STST
Time Frame: 8 weeks
the number of repetitions performed in the 1-min sit-to-stand test (rep.)
FVC
Time Frame: 8 weeks
forced vital capacity tested in pulmonary function test (Liters)
Distance-Saturation Product (DSP)
Time Frame: 8 weeks
the product of distance walked and lowest oxygen saturation during the 6-min walk test (m%)
FEV1/FVC
Time Frame: 8 weeks
forced expiratory volume in 1 second divided by forced vital capacity in pulmonary function test (%)
Predicted distance
Time Frame: 8 weeks
percentage of the predicted 6 minute walk test distance (%pred)
5-rep STST
Time Frame: 8 weeks
the complete time for the 5-repetition sit-to-stand test (sec)
Muscle strength test2
Time Frame: 8 weeks
maximal force output for quadriceps muscle (lbs)
X-ray score
Time Frame: 8 weeks
the evaluation of the chest radiography based on the sputum impaction score, scores ranging from 0 to 18. A decrease in score represented an improvement in sputum in each area.
modified Medical Research Council (mMRC)
Time Frame: 8 weeks
questionnaire of dyspnea, scores ranging from 0 (low degree of dyspnea) to 4 (high degree of dyspnea)
Saint George Respiratory Questionnaire (SGRQ)
Time Frame: 8 weeks
questionnaire of overall health, daily life, and perceived well-being, scores ranging from 0 (no health impairment) to 100 (maximum health impairment)
FEV1
Time Frame: 8 weeks
forced expiratory volume in 1 second in pulmonary function test (Liters)
FEV1(% pred)
Time Frame: 8 weeks
percentage of predicted FEV1 value (% pred)
6 min walk distance
Time Frame: 8 weeks
the distance walked in 6 minutes (m)
Muscle strength test1
Time Frame: 8 weeks
Maximal force output for biceps femoris muscle (lbs)
Sputum self-assessment scale
Time Frame: 8 weeks
questionnaire of sputum volume, it contained three items (0-25 mL/d, 25-50 mL/d, and 50-100 mL/d) as a checklist
Secondary Outcomes
No secondary outcomes reported