The Effect of Adding Intrathecal Dexmedetomidine on Shoulder Tip Pain During Laparoscopic Ovarian Cystectomy Under Bupivacaine Spinal Anaesthesia. Randomised Controlled Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- occurrence shoulder tip pain
研究概览
简要总结
Conventionally General anaesthesia remains the choice for the majority of open abdominal surgical procedures, and regional anaesthesia is preferred only for patients who are at high risk under general anaesthesia . The main reason for selecting spinal anaesthesia as the first choice for laparoscopic cases was its advantages over general anaesthesia which include uniform total muscle relaxation, a conscious patient, economical, relatively uneventful recovery, pain free early postoperative period and the protection from potential complications of general anaesthesia. The main debatable point, however, seems to be the status of respiratory parameters among the two modes of anaesthesia during laparoscopic surgery. In this context it can be stated that spontaneous physiological respiration during spinal anaesthesia would always be better than an assisted respiration as in general anaesthesia.
The pneumo-peritoneum induced rise in intra-abdominal pressure including pressure on the diaphragm and carbon dioxide induced peritoneal irritation are the factors to be considered
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 40 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Elective gynaecological laparoscopic surgery
- •Age 20-45 yrs
- •Suspected surgery time 30 minutes
- •Inflation pressure <13 Cm H20
排除标准
- •Contraindications to regional block (infection at the needle insertion site)
- •Altered conscious level.
- •Pregnancy
- •Body mass index >35
- •Height <155 cm
- •Patients who have difficulty understanding the study protocol
研究组 & 干预措施
control group
will receive 3.5 ml (17.5 mg) hyperbaric Bupivacaine + 0.5 ml saline
干预措施: Normal saline (Drug)
Dexmedetomidine group
will receive 3.5 ml (17.5 mg) hyperbaric Bupivacaine + 0.5 ml dexmedetomidine (0.5 mic)
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
occurrence shoulder tip pain
时间窗: 48 hours
次要结局
- intraoperative haemodynamic stability, et co2, sao2.(2 hours)
研究者
Rasha Hamed
Lecturer of anesthesia
Assiut University
