Using a Simplified Tool to Predict Lung Cancer Screening (LCS) Eligibility: Experiment to Test Effects of Messaging on Response Rates
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 6,125
- Locations
- 1
- Primary Endpoint
- Full Survey Completion
Study Overview
Brief Summary
The primary purpose of this study evaluate if different messaging impacts response rates to a brief survey (i.e., the simplified eligibility tool) that is designed to estimate pack-year eligibility for lung cancer screening (LCS). This will help inform the best way to increase response rates to the tool in future intervention studies designed to increase LCS, and expand upon survey methodology in general.
Detailed Description
Despite growing evidence that lung cancer screening (LCS) reduces lung cancer-specific mortality, LCS across the United States is remarkably low. This is due in part to challenges with identifying adults who meet eligibility criteria for lifetime smoking intensity (i.e., 20 pack-years or greater), which is often missing from the electronic medical record. We have developed a simplified eligibility tool that has shown accuracy in estimating pack-years. But given the potential for low response rates, there is a great need to identify effective strategies to increasing response rates equitably prior to using it in practice or in future studies. The primary purpose of this study evaluate if different messaging impacts response rates to a brief survey (i.e., the simplified eligibility tool) that is designed to estimate pack-year eligibility for lung cancer screening (LCS). This will help to identify the best way to increase response rates to the tool in future intervention studies designed to increase LCS, and expand upon survey methodology in general.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Factorial
- Primary Purpose
- Health Services Research
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 50 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •meet age eligibility (50-80 years old) for LCS based on 2021 USPSTF guidelines; and
- •have completed at least one primary care visit at Penn Medicine in 2020-2025
Exclusion Criteria
- •have a documented history of lung cancer;
- •have a documented history of completing LCS at Penn Medicine;
- •are listed as not wanting to be contacted or solicited for research; or
- •do not otherwise meet inclusion criteria.
Arms & Interventions
Arm 8 (Introductory Message B + Tobacco Use Message B)
Participants will receive two framed messages (BB)
Intervention: Framed Tobacco Use Message B (Behavioral)
Arm 9 (Introductory Message C + Tobacco Use Message A + Incentive)
Participants will receive two framed messages (CA) plus an incentive
Intervention: Framed Introductory Message C (Behavioral)
Arm 9 (Introductory Message C + Tobacco Use Message A + Incentive)
Participants will receive two framed messages (CA) plus an incentive
Intervention: Framed Tobacco Use Message A (Behavioral)
Arm 9 (Introductory Message C + Tobacco Use Message A + Incentive)
Participants will receive two framed messages (CA) plus an incentive
Intervention: Financial Incentive (Behavioral)
Arm 1 (Introductory Message A + Tobacco Use Message A + Incentive)
Participants will receive two framed messages (AA) plus an incentive
Intervention: Framed Introductory Message A (Behavioral)
Arm 1 (Introductory Message A + Tobacco Use Message A + Incentive)
Participants will receive two framed messages (AA) plus an incentive
Intervention: Framed Tobacco Use Message A (Behavioral)
Arm 1 (Introductory Message A + Tobacco Use Message A + Incentive)
Participants will receive two framed messages (AA) plus an incentive
Intervention: Financial Incentive (Behavioral)
Arm 2 (Introductory Message A + Tobacco Use Message A)
Participants will receive two framed messages (AA)
Intervention: Framed Introductory Message A (Behavioral)
Arm 2 (Introductory Message A + Tobacco Use Message A)
Participants will receive two framed messages (AA)
Intervention: Framed Tobacco Use Message A (Behavioral)
Arm 10 (Introductory Message C + Tobacco Use Message A)
Participants will receive two framed message (CA)
Intervention: Framed Introductory Message C (Behavioral)
Arm 10 (Introductory Message C + Tobacco Use Message A)
Participants will receive two framed message (CA)
Intervention: Framed Tobacco Use Message A (Behavioral)
Arm 3 (Introductory Message A + Tobacco Use Message B + Incentive)
Participants will receive two framed messages (AB) plus an incentive
Intervention: Framed Introductory Message A (Behavioral)
Arm 3 (Introductory Message A + Tobacco Use Message B + Incentive)
Participants will receive two framed messages (AB) plus an incentive
Intervention: Framed Tobacco Use Message B (Behavioral)
Arm 3 (Introductory Message A + Tobacco Use Message B + Incentive)
Participants will receive two framed messages (AB) plus an incentive
Intervention: Financial Incentive (Behavioral)
Arm 4 (Introductory Message A + Tobacco Use Message B)
Participants will receive two framed messages (AB)
Intervention: Framed Introductory Message A (Behavioral)
Arm 4 (Introductory Message A + Tobacco Use Message B)
Participants will receive two framed messages (AB)
Intervention: Framed Tobacco Use Message B (Behavioral)
Arm 5 (Introductory Message B + Tobacco Use Message A + Incentive)
Participants will receive two framed messages (BA) plus an incentive
Intervention: Framed Introductory Message B (Behavioral)
Arm 5 (Introductory Message B + Tobacco Use Message A + Incentive)
Participants will receive two framed messages (BA) plus an incentive
Intervention: Framed Tobacco Use Message A (Behavioral)
Arm 5 (Introductory Message B + Tobacco Use Message A + Incentive)
Participants will receive two framed messages (BA) plus an incentive
Intervention: Financial Incentive (Behavioral)
Arm 6 (Introductory Message B + Tobacco Use Message A)
Participants will receive two framed messages (BA)
Intervention: Framed Introductory Message B (Behavioral)
Arm 6 (Introductory Message B + Tobacco Use Message A)
Participants will receive two framed messages (BA)
Intervention: Framed Tobacco Use Message A (Behavioral)
Arm 7 (Introductory Message B + Tobacco Use Message B + Incentive)
Participants will receive two framed messages (BB) plus an incentive
Intervention: Framed Introductory Message B (Behavioral)
Arm 7 (Introductory Message B + Tobacco Use Message B + Incentive)
Participants will receive two framed messages (BB) plus an incentive
Intervention: Framed Tobacco Use Message B (Behavioral)
Arm 7 (Introductory Message B + Tobacco Use Message B + Incentive)
Participants will receive two framed messages (BB) plus an incentive
Intervention: Financial Incentive (Behavioral)
Arm 8 (Introductory Message B + Tobacco Use Message B)
Participants will receive two framed messages (BB)
Intervention: Framed Introductory Message B (Behavioral)
Arm 11 (Introductory Message C + Tobacco Use Message B + Incentive)
Participants will receive two framed messages (CB) plus an incentive
Intervention: Framed Introductory Message C (Behavioral)
Arm 11 (Introductory Message C + Tobacco Use Message B + Incentive)
Participants will receive two framed messages (CB) plus an incentive
Intervention: Framed Tobacco Use Message B (Behavioral)
Arm 11 (Introductory Message C + Tobacco Use Message B + Incentive)
Participants will receive two framed messages (CB) plus an incentive
Intervention: Financial Incentive (Behavioral)
Arm 12 (Introductory Message C + Tobacco Use Message B)
Participants will receive two framed messages (CB)
Intervention: Framed Introductory Message C (Behavioral)
Arm 12 (Introductory Message C + Tobacco Use Message B)
Participants will receive two framed messages (CB)
Intervention: Framed Tobacco Use Message B (Behavioral)
Outcomes
Primary Outcomes
Full Survey Completion
Time Frame: 7 days
The proportion of participants that answers all three survey questions via text message among all those randomized.
Secondary Outcomes
- Partial Survey Completion(7 days)
Investigators
Katharine Rendle
Assistant Professor
Abramson Cancer Center at Penn Medicine