Optimal initial and maintenance doses of ergocalciferol supplementation for treatment of hypovitaminosis D in Thai adults: A randomized, double-blinded dose-comparison study

Phase 1

• Conditions: Vitamin D deficiency; Ergocalciferol; Vitamin D supplementation; Vitamin D insufficiency; Hypovitaminosis D

• Registration Number: TCTR20170226001
• Lead Sponsor: Ratchadaphiseksomphot Endowment Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-02-26
• Study Completion: 2017-11-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

Thai Adult 18 years of age and over
Bodymass index within 18 - 30 kg/square meter
Vitamin D level (25(OH)D) less than 30 ng/ml

Exclusion Criteria

Renal insufficiency, eGFR less than 30 ml/min
Nephrotic syndrome
Renal calculi
Cirrhosis
Malabsorptive condition
Cancer
Hypercalcemia
Receive any vitamin D supplement or other drug which interfere with vitamin D metabolism esp. carbamazepine, phenobarbital, phenytoin, steroid, lipase inhibitor, bile acid sequestrant, before enrollment within 6 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage of vitamin D achievement equal or over 30 ng/ml 3 month and 6 month post vitamin D prescription Percentage

Secondary Outcome Measures

Name	Time	Method
Percentage of vitamin D achievement equal or over 30 ng/ml in each group 3 month and 6 month post vitamin D prescription Percentage