MedPath

Effects of Bushen Huoxue method in fracture healing after biplanar open wedge high tibial osteotomy

Phase 1
Recruiting
Conditions
Knee osteoarthritis
Registration Number
ITMCTR2000003676
Lead Sponsor
Xuanwu Hospital Capital Medical University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Patients who meet the OA diagnostic criteria;
2. Patients with aged >=50 and <=70 years old;
3. Agree to operate on the same operator (operated by a doctor with senior professional title, adopting unified standardized OWHTO technology, 3D printing osteotomy guide plate and internal fixation materials of the same manufacturer);
4. Patients who are able to cooperate with specific treatment: those who have specified time for reexamination and regular rehabilitation exercise, and complete data.

Exclusion Criteria

1. People with allergies and allergic to oral Chinese patent medicines;
2. Suffering from endocrine diseases such as diabetes, hyperthyroidism, and hyperparathyroidism;
3. Liver and kidney insufficiency, and have used hormones or other drugs that affect bone metabolism within six months;
4. Suffering from rheumatoid arthritis, bone tumor or Paget disease;
5. It is difficult to determine the effect of medication without following the doctor's order

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
X-ray;
Secondary Outcome Measures
NameTimeMethod
Ca2+;KSS score;ß-CTX;PINP;Visual Analogue Scale/Score;ALP;CT;BMP;
© Copyright 2025. All Rights Reserved by MedPath