Subdissociative-Dose Ketamine versus Fentanyl for Adjunctive Analgesic during Propofol-Based Sedation for Esophagogastroduodenoscopy ( EGD) and Colonoscopy in Elderly Patients: A Prospective Randomized Control Study
Phase 4
Completed
- Conditions
- total propofol dosestable hemodynamictime to Aldrete score 9serious adverse eventEGD-Colonoscopeelderly patientketamine
- Registration Number
- TCTR20140703003
- Lead Sponsor
- Golden Jublee Medical Center, Mahidol University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 102
Inclusion Criteria
Patients will be enrolled if they were 65 90 years old who underwent elective EGD colonoscopy under intravenous sedation with Propofol based
Patients who were ASA I -III
Exclusion Criteria
Had history of severe cardiac disease ejection fraction 30
allergy to anesthetics
Had history of neurologic disease seizure glaucoma
Had history of chronic opioid used or sedative drugs
morbid obesity BMI 35
poorly control hypertension severe hypertension SBP 160 mmHg
Had history of psychiatric disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method total propofol dose at end of procedure Total dose of propofol (mg)
- Secondary Outcome Measures
Name Time Method time to aldrete score 9 at time that patient had aldrete score 9 in recovery room minute since end of operation to patient had aldrete score 9,hemodynamic response between group baseline, after induction, then every 5 minute until 60 minute BP, RR, SpO2