Pulmonary Rehabilitation for Idiopathic Pulmonary Fibrosis

Not Applicable

Completed

• Conditions: Idiopathic Pulmonary Fibrosis
• Interventions: Other: Pulmonary rehabilitation

• Registration Number: NCT00692796
• Lead Sponsor: National Jewish Health

Brief Summary

The purpose of this study is to determine the effects of Pulmonary Rehabilitation (PR) on shortness of breath, exercise capacity, symptom control, mental health, cognitive function, and quality of life in patients with Idiopathic Pulmonary Fibrosis (IPF). Pulmonary rehabilitation has already been shown to benefit patients with other chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD). We believe that pulmonary rehabilitation will benefit patients with IPF as well.

Detailed Description

The goals of this project are to assess the effect of PR on a number of important outcomes in patients with IPF. Once enrolled in the study, subjects will complete a battery of questionnaires and tests that assess symptoms, quality of life, cognition, and mental health, and then subjects will complete a six week outpatient PR program (at National Jewish Medical and Research Center or other PR programs). Subjects will complete the same battery of questionnaires and tests immediately after completion of the PR program and again six months later.

Study Timeline

• Study Start: 2008-04
• Study First Submitted: 2008-06-04
• Study First Submitted QC: 2008-06-04
• Study First Posted: 2008-06-06
• Primary Completion: 2010-03
• Study Completion: 2010-03
• Status Verified: 2017-03
• Last Update Submitted: 2017-03-27
• Last Update Posted: 2017-03-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Age 40 years or older
• Diagnosis of IPF according to American Thoracic Society criteria

Exclusion criteria:

• Patients who have completed a PR program within the last two years
• Patients with unstable medical conditions that would make PR unsafe

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
1	Pulmonary rehabilitation	-

Primary Outcome Measures

Name	Time	Method
Exercise capacity	6 weeks and again at 6 months

Secondary Outcome Measures

Name	Time	Method
Anxiety	6 weeks and again at 6 months
Depression	6 weeks and again at 6 months
Cognition	6 weeks and again at 6 months
Quality of life	6 weeks and again at 6 months
Fatigue	6 weeks and again at 6 months

Trial Locations

Locations (1)

National Jewish Medical and Research Center; 🇺🇸 Denver, Colorado, United States