Healing Effect of Gastric mucosal Lesion of patient with Osteoarthritis or Rheumatism by Cox2-Inhibitor and Anti ulcer agent(Rebamipide) combination therapy.
Not Applicable
- Conditions
- rheumatic arthritis osteoarthritis lumbago
- Registration Number
- JPRN-UMIN000002112
- Lead Sponsor
- Department of Orthopaedic Surgery, Mie University Hospital Department of Gastroenterology and Hepatology, Mie University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Not provided
Exclusion Criteria
History of gastrointestinal surgery Presence of gastroesophageal reflex disease (GERD) Presence of malignancy Presence of gastrointestinal bleeding or gastrointestinal ulcer Presence of aspirin-induced asthma Pcesence of severe cardiac disorder, renal disorder or liver disorder Impossibility of endoscopic examination Presence of allergy of celecoxib or rebamipide History of percutaneous coronary revascularization Pregnancy and lactation Impossibility of discontinuation of proton pump inhibitor or histamine-2 receptor antagonist Administration of NSAID that excludes aspirin Patient who doctor judged improper
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method An incidence of gastrointestinal bleeding or endoscopic ulcer
- Secondary Outcome Measures
Name Time Method