Serum Level of Bioactive Mediators and Urinary Biopyrins in Psoriasis

• Conditions: Psoriasis

• Registration Number: NCT03889938
• Lead Sponsor: Assiut University

Brief Summary

1. Assess the level of lipid mediators in patients with psoriasis

2. Assess the urinary level of biopyrins as New marker of oxidative stress in patients with psoriasis

3. Correlate the serum level of bioactive lipid mediators and urinary level of biopyrins with Psoriasis Area and Severity Index

Detailed Description

Psoriasis is acommon immune mediated inflammatory skin disorder of complex pathomechanisms which is generically conditioned and influenced by environmental factors

Study Timeline

• Status Verified: 2019-03
• Study First Submitted: 2019-03-22
• Study First Submitted QC: 2019-03-24
• Last Update Submitted: 2019-03-24
• Study First Posted: 2019-03-26
• Last Update Posted: 2019-03-26
• Study Start: 2019-04-01
• Primary Completion: 2020-04
• Study Completion: 2020-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• age from12 to 80 and both sex

Exclusion Criteria

• patients with other dermatological disorders

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the serum level of bioactive lipid mediators in patients with psoriasis	1 month	Bioactive lipid mediators (LMs) are potent compounds reported to play a role in the development and resolution of inflammation.