ACTRN12607000415404
Completed
Phase 3
A randomized controlled trial in adults with knee osteoarthritis to determine the effect of high dose fish oil compared with low dose fish oil on symptomatic and structural outcomes.
ational Health and Medical Research Council (NHMRC)0 sites200 target enrollmentAugust 17, 2007
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Knee osteoarthritis
- Sponsor
- ational Health and Medical Research Council (NHMRC)
- Enrollment
- 200
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adults with symptomatic knee osteoarthritis, defined using American College of Rheumatology (ACR) criteria. Symptomatic knee osteoarthritis (score of \>4 on at least 1 pain dimension of the Western Ontario and McMaster Osteoarthritis Index (WOMAC).
Exclusion Criteria
- •Dementia or inability to give informed consent; grade 4 (endstage) xray changes in the symptomatic knee; planned knee joint replacement surgery; daily fish oil ingestion \>\=10mL or 9 standard capsules for the preceding 3 months; contra\-indications to MRI.
Outcomes
Primary Outcomes
Not specified
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