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Clinical Trials/NCT03506074
NCT03506074
Completed
Not Applicable

Flavor Perception in the Population of Campania Region, Italy

Federico II University0 sites420 target enrollmentOctober 1, 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Weight, Body
Sponsor
Federico II University
Enrollment
420
Primary Endpoint
Flavor score
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

Dietary choices are influenced by several factors, including physiological, social or genetic factors. Among these, flavor is the most important determinant modulating the preferences versus specific foods.

Flavor perception is the result from the sensory integration of taste and odor properties of food.

Aim of the present study was to assess flavor abilities in a large population using a validated perceptive test.

Detailed Description

This protocol investigates flavor perception using the flavor test, a specific test to assess the retro-nasal olfactory function. A decrease in taste and smell abilities can result in loss of appetite, inadequate dietary intake and malnutrition. Several diseases and conditions have been associated with taste disorders and a decline in gustatory function is very common in the elderly. The flavor test was previously developed, validated and patented by our group. It consists of a series of 20 aromatic extracts, corresponding to routine dietary use flavors for Italian people. Each tastant, originally stored in a 30 mL amber bottle, is diluted in distilled water and stored at 4 °C, then it is kept at room temperature for 20 min before administration. An aliquot of approximately 0,5 mL of each tastant is administered in the oral cavity using a 3mL Transfer Pipet and left for approximately 5 seconds; the mouth is then rinsed twice with distilled water before the administration of the following tastant. At each administration, participants are invited to identify the aromatic by making a choice from 5 proposed items. A total of 21 aromatics (including one blank) are administered sequentially. The flavor score (FS) is calculated as the sum of correctly identified aromatics and ranged from 0 to 21.

Registry
clinicaltrials.gov
Start Date
October 1, 2014
End Date
October 30, 2017
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Federico II University
Responsible Party
Principal Investigator
Principal Investigator

Paolo Emidio Macchia

Prof.

Federico II University

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 18 years

Exclusion Criteria

  • Allergies, drug usage

Outcomes

Primary Outcomes

Flavor score

Time Frame: Immediately after the test administration flavor score was calculated

A flavor score (1-21) was measured in all the studied subjects using the Flavor test

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