Routine Iron Prophylaxis During Pregnancy - Effects on Maternal and Child Health in Maputo City and Province (Mozambique)
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 4,326
- 试验地点
- 1
- 主要终点
- Preterm delivery
研究概览
简要总结
Comparison of two policies of iron administration during pregnancy in regard to health and program feasibility in an area with endemic malaria and high prevalence of HIV infection. The policies are: 1) routine iron prophylaxis, 2) screening and therapy with iron.
详细描述
Aim of the study:
Comparison of two policies of iron administration during pregnancy in regard to health of the mother and infant and program feasibility. The two groups compared are:
- Routine iron prophylaxis
- Screening of anaemia and therapy with iron
Hypothesis: group 2 will have better health outcomes.
Study groups:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnant women at their first prenatal visit
排除标准
- •Women under 18 years, high obstetric risk pregnancies
研究组 & 干预措施
routine iron prophylaxis
giving 60 mg ferrous sulphate daily (+folic acid)
干预措施: Two policies of iron prophylaxis (Drug)
screening and therapy
doing Hb measurement on each visit, Hb>9g/dl giving only folic acid, Hb<9g/dl giving 60-120 mg of ferrous sulphate daily (+folic acid)
干预措施: Two policies of iron prophylaxis (Drug)
结局指标
主要结局
Preterm delivery
时间窗: Until birth
Birth \<37 gestational weeks
Low birth weight
时间窗: At birth
weight \<2500g
次要结局
- perinatal mortality, complications during pregnancy and birth(pregnancy and neonatal period)
研究者
Elina Hemminki
MD, Research Professor, THL
National Istitute For Health and Welfare, Finland