Clinical trial of Lactiplantibacillus plantarum KF511 for respiratory symptoms
- Conditions
- Diseases of the respiratory system
- Registration Number
- KCT0009249
- Lead Sponsor
- Jeonbuk National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 100
1) Aged 19 to 80 years
2) A person who has two or more symptoms of persistent respiratory symptoms (cough, sputum, dyspnoea or chest pain) for at least one month
3) Voluntary agreement to participate in the clinical trials and provision of informed consent
1) Smoker
2) Forced expiratory volume in the first second/ Forced vital capacity (FEV1/FVC) ratio (post-bronchodilator) < 70% or FVC< 80%
3) History of underlying chronic respiratroy disease such as COPD or asthma
4) Clinically significant lung disease findings on chest X-ray (bronchiectasis, cystic fibrosis, bronchiolitis obliterans, active tuberculosis, pneumothorax, emphysema, etc.)
5) History of acut respiratory infection, and influenza etc. within 4 weeks
6) Administration of antitussive, apophlegmatic, steroids, and antibiotics etc. within 4 weeks
7) Intake of probiotics within 2 weeks before screening visit
8) Allergic or hypersensitivity to drug and any of the ingredients in the test products (probiotics)
9) History of alcohol or substance abuse
10) Participation in other clinical trials within 3 months
11) AST or ALT > 3 fold of normal range or serum creatinine > 2.0 mg/dl
12) Pregnant, planning to become pregnant, or breast-feeding
13) Laboratory test, medical or psychological conditions deemed by the investigators to interfere with successful participation in the studya n
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method