ISRCTN42862937
已完成
未知
Protocol for a longitudinal, cohort study to evaluate Reactivation of Herpesviruses and Inflammation as Cardiovascular and Cerebrovascular risk factors in Antiretroviral initiators, in an African HIV population (RHICCA)
概览
- 阶段
- 未知
- 干预措施
- 未指定
- 疾病 / 适应症
- Cardiovascular and cerebrovascular disease
- 发起方
- GlaxoSmithKline
- 入组人数
- 1090
- 状态
- 已完成
- 最后更新
- 3年前
概览
简要总结
2019 Protocol article in https://pubmed.ncbi.nlm.nih.gov/31515413/ protocol (added 05/10/2020)
研究者
入排标准
入选标准
- •1\. Aged \=\> 35 years
- •2\. Resident in Blantyre
- •3\. HIV\-infected patients must further be ART\-naïve or initiated ART \<10 days prior to enrolment
- •4\. Initiating standard first\-line ART (in Malawi this is: TDF/3TC/EFV)
- •5\. Adult controls must further be HIV uninfected
排除标准
- •1\. Clinical history of CVD/CBD
- •2\. Pregnant
- •3\. Critically ill or have symptomatic anaemia at enrolment
- •4\. Enrolled in an intervention study
结局指标
主要结局
未指定
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