ISRCTN45938399已完成3 期
A multicentre randomised trial of radical radiotherapy with carbogen in the radical radiotherapy of locally advanced bladder cancer
Cancer Research UK (CRUK) (UK)0 个研究点目标入组 0 人开始时间: 2001年7月1日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
研究概览
简要总结
2009 Results article in https://www.ncbi.nlm.nih.gov/pubmed/18992952 early results 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33689854/ 10-year results (added 11/03/2021)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Aged 18 or over
- •2. Histologically proven transitional cell carcinoma of the bladder
- •3. Muscle invasive carcinoma (Stage T2 or T3) of any grade; G3 superficial bladder cancer (T1) or prostatic invasion T4a
- •4. Ability to give informed consent
- •5. Capable of complying with the use of a closed breathing system delivering carbogen through either a mask or a mouthpiece with nasal clip
- •6. No squamous or adenocarcinoma of the bladder
- •7. No locally advanced T4b carcinoma
- •8. No presence of distant metastasis or enlarged lymph nodes on Computed Tomography (CT) staging scan of the pelvis
- •9. No co-existing respiratory disease that contra-indicates delivery of 95% oxygen
- •10. No impaired renal or hepatic function
- •11. No ischeamic heart disease or peripheral vascular disease requiring treatment with diuretics or ACE inhibitors
排除标准
- •Not provided at time of registration
研究者
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