Treatment of Negative Symptoms and Schizophrenia
Phase 1
Completed
- Conditions
- Schizophrenia
- Interventions
- Device: transcranial direct current stimulation
- Registration Number
- NCT02204787
- Lead Sponsor
- University Hospital, Montpellier
- Brief Summary
The aim of this study is to evaluate the therapeutic efficacy of a neuromodulation technique, tDCS (transcranial direct current stimulation) used as a complementary treatment on negative symptoms. 60 patients will be randomized into two groups (active tDCS vs sham tDCS) and will be assessed after the intervention, 1 and 3 months after.Secondary outcomes shall include neuropsychological assessment, general symptomatology, extrapyramidal symptoms and social functioning.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Schizophrenia with prominent negative symptoms
Exclusion Criteria
- other psychiatric or neurological diseases
- specific tDCS limitations
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description active tDCS transcranial direct current stimulation Transcranial Direct Current Stimulation : 10 sessions twice a day during 5 days, with a 2 mA intensity during 20 minutes. Sham tDCS transcranial direct current stimulation Transcranial Direct Current Stimulation : 10 sessions twice a day during 5 days, with a sham stimulation during 20 minutes. Initial stimulation followed by turning off the device as to ensure blinding.
- Primary Outcome Measures
Name Time Method Scale for the Assessment of Negative Symptoms up to 3 months after intervention
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UH Montpellier
🇫🇷Montpellier, France