Treatment of Negative Symptoms and Schizophrenia

Phase 1

Completed

• Conditions: Schizophrenia

• Registration Number: NCT02204787
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

The aim of this study is to evaluate the therapeutic efficacy of a neuromodulation technique, tDCS (transcranial direct current stimulation) used as a complementary treatment on negative symptoms. 60 patients will be randomized into two groups (active tDCS vs sham tDCS) and will be assessed after the intervention, 1 and 3 months after.Secondary outcomes shall include neuropsychological assessment, general symptomatology, extrapyramidal symptoms and social functioning.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-04-01
• Study First Submitted: 2014-07-29
• Study First Submitted QC: 2014-07-29
• Study First Posted: 2014-07-30
• Status Verified: 2017-11
• Primary Completion: 2018-10-26
• Study Completion: 2018-10-26
• Last Update Submitted: 2022-12-13
• Last Update Posted: 2022-12-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Schizophrenia with prominent negative symptoms

Exclusion Criteria

• other psychiatric or neurological diseases
  • specific tDCS limitations

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Scale for the Assessment of Negative Symptoms	up to 3 months after intervention

Trial Locations

Locations (1)

UH Montpellier; 🇫🇷 Montpellier, France