Investigation of Ultrasound Elastographic Techniques in Soft Tissue Pathology

• Conditions: Tissue Pathology
• Interventions: Procedure: SWUE

• Registration Number: NCT02086357
• Lead Sponsor: The Leeds Teaching Hospitals NHS Trust

Brief Summary

Ultrasound (US)tissue elastography has recently been found to have a number of clinical applications in the assessment of soft tissue disease for example, in breast and thyroid pathology. There are few current studies exploring its use in musculoskeletal pathology, particularly a new technique called sheer wave ultrasound elastography (SWUE).

Magnetic Resonance (MR) elastography has shown wide reaching applications in orthopaedics, sports medicine and rheumatology and SWUE may have the potential to also demonstrate clinical effectiveness in these areas.

Our aim is to explore the effectiveness of this technique in the assessment of musculoskeletal pathology.

Participants will be recruited through current referral protocols and would undergo an additional elastographic investigation in addition to their standard US examination. This investigation will be conducted within the musculoskeletal US department at Chapel Allerton Hospital by trained musculoskeletal specialists. The study will be conducted over a period of approximately 24 months with quarterly review during this time.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-07
• Study First Submitted: 2014-01-23
• Study First Submitted QC: 2014-03-11
• Study First Posted: 2014-03-13
• Status Verified: 2015-02
• Last Update Submitted: 2015-02-19
• Last Update Posted: 2015-02-23
• Primary Completion: 2016-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• Have clinical symptoms and signs of soft tissue pathology
• Be able to give consent
• Be over 16 years of age

Exclusion Criteria

• Unable to give consent
• 16years of age or less
• Multifactorial soft tissue pathology

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
SWUE	SWUE	-

Primary Outcome Measures

Name	Time	Method
Clinical effectiveness of Sheer wave ultrasound elastography (SWUE) in the assessment of soft tissue pathology	Baseline to 24 months	Ability of SWUE to accurately detect soft tissue pathology when compared with standard ultrasound techniques.

Trial Locations

Locations (1)

Leeds Teaching Hospital NHS Trust; 🇬🇧 Leeds, United Kingdom