NCT00333346已完成2 期
Tramadol iv. : Influence of Dose and Dose Intervals on Therapeutic Accuracy and Side Effects When Used for Postoperative Pain Relief in Ambulatory Surgery
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- Time course of pain relief
研究概览
简要总结
The aim of this study is to compare the administration of 1 unit dose of 100 mg tramadol intravenously versus multiple smaller dosages of tramadol during the first 6 hours post-operatively and to investigate the time course and accuracy of pain relief versus the onset and duration of side-effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I and II female or male patients
- •Aged 18-70 years
- •Scheduled for ambulatory surgery requiring postoperative pain medication.
排除标准
- •Weight less than 70% or more than 130% of ideal body weight
- •Neurological disorder
- •Recent use of psycho-active medication, including alcohol
- •Patients suffering from chronic pain receiving pre-operative pain medication including NSAID's
- •Use of chronic anti-emetic medication, use of chronic corticoid therapy
结局指标
主要结局
Time course of pain relief
Accuracy of pain relief
Onset of side-effects
Duration of side-effects
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
进行中（未招募）
不适用
Tramadol iv. : influence of dose and dose intervals on therapeutic accuracy and side effects when used for postoperative pain relief in ambulatory surgeryASA I and IIEUCTR2006-002901-30-BEniversity Hospital Ghent200
已完成
3 期
A Study Comparing the Effectiveness and Safety of Varying Dose Strengths (100, 200, 300 and 400 mg) of Extended-release Tramadol HCl With Placebo for the Treatment of Osteoarthritis(OA) of the Knee and/or HipChronic PainNCT00325858Bausch Health Americas, Inc.1,000
尚未招募
4 期
The effect of rate of administration of tramadol on incidence of post operative nausea and vomiting after any surgical operation for which significant postoperative pain is expectedACTRN12606000201572ANZCA (australaian and New Zealand College of Anaesthetists)150
已完成
4 期
Comparison of Tramadol Orally Versus an Optimized Dose of Intravenous Tramadol for Postoperative Pain Relief in Ambulatory SurgeryPainNCT00735748University Hospital, Ghent195
已完成
3 期
A Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 mg, 200 mg and 300 mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)Chronic PainNCT00348452Bausch Health Americas, Inc.1,000