The Effect of 12-week Aerobic and Lower Extremity Resistance Exercises on Healing of Foot Ulcers in Type 2 Diabetic Patients

Iran University of Medical Sciences0 个研究点目标入组 26 人开始时间: 待定最近更新: 2021年6月21日

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•Type II DM according to ADA criteria for less than 20 years
•Receiving medical care (diet, oral agents, insulin) throughout the disease course
•Stable hypoglycemic medications (type & dosage) within the last 2 months
•Existence of at least one foot ulcer with Wound Surface Area = 16 cm2
•The ulcer must be classified as grade 2, stage A or C under the UTCS
•Stable anti inflammatory drugs (drugs prescribed to control HTN or hyperlipidemia) during the last 3 months
•At least 18 years of age
•0.7 = ABI = 1.4
•6.5% = HbA1C = 9.5%
•100 = FBS = 250 mg/dl
•Sedentary lifestyle for the last 6 months

•Cognitive or mental deficit
•Wound treatments other than standard care (deemed to be required by the physician) such as growth factors, NPWT, hyperbaric oxygen, special dressings, etc.
•Ulcer requiring surgical operations other than debridement
•Non-diabetic ulcers such as electrical, chemical or radiation burns, etc.
•Pregnancy or breast feeding
•Infection or OM
•Critical limb ischemia or lower extremity gangrene
•Proliferative retinopathy or history of retinal detachment
•Moderate or severe kidney disease
•History of major lower extremity amputation
•Severe liver disease
•Uncontrolled HTN or BP higher than 160/95 mmHg
•Life-threatening disease such as malignancy
•History of DVT during the last 6 months
•Active cellulitis or collagen vascular disease
•Active Charcot
•Present history of smoking or alcoholism
•Immunodeficiency caused by immunosuppressant usage or chemotherapy during the past 2 months, radiotherapy within the last 4 months or systemic diseases
•Presence of any overt cardiovascular condition diagnosed by cardiologist that prevents the patient from performing vigorous activities
•Any kind of disease or condition (orthopedic, neurologic, pulmonary, arthritis, etc.) that limits or contraindicates physical activity
•Presence of any condition considered as absolute contraindication for physical activity by the ACSM’s guideline
•Participating in any experimental or non-experimental program that requires regular physical activity

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