BEST DOSE AMONG THE THREE

Completed

• Conditions: Diseases of the eye and adnexa,

• Registration Number: CTRI/2018/05/014305
• Lead Sponsor: INSTITUTIONAL

Brief Summary

Preoperative anxiety in children is a major concern to the pediatric anesthesiologist. Children may become overtly uncooperative at the time of seperation from parents , venipuncture, or mask application.

Preinduction techniques ,aimed at reducing preoperative anxiety.

For sedative medications ketamine ,midazolam, fentanyl have been used with variable results. Dexmedetomedine is a highly selective alpha-2 adrenoceptor agonist that provides sedation, anxiolysis and analgesic effects without causing respiratory depression.

In children it is a difficult and even traumatic to obtain iv acess and lack of cooperation like swallowing for oral route makes the transmucosal route a more preferred one.

We plan to undertake this to objectively assess and compare the efficacy of these three doses of dexmedetomedine as premedications by these objective validated scoring system.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-03
• Last Update Posted: 2021-06-07

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

AGE 1-6 YRS ASA GRADE ONE AND TWO PATIENT UNDERGOING GENERAL ANESTHESIA.

Exclusion Criteria

• KNOWN ALLERGY OR HYPER SENSITIVITY TO DEXMEDETOMEDINE.
• ABERRANT NASAL ANATOMY.
• ACUTE OR CHRONIC NASAL TRAUMA THAT MAY PRECLUDE ADEQUATE INTRANASAL DELIVERY OF DRUG.
• ANTICIPATED DIFFICULT AIRWAY.
• LIVER DYSFUNCTION.
• CARDIAC ARRHYTHMIAS, CONGENITAL HEART DISEASE ,MENTL RETARDATION.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TO EVALUATE AND COMPARE EFFICACY OF THREE DIFFERENT DOSES OF INTRANASAL(ROUTE) DEXMEDETOMEDINE FOR PREMEDICATION IN CHILDREN FOR PREOPERATIVE ANXIETY USING THE mYPAS SCALE TAKING ONE BASELINE THEN AFTER ,30MIN,45MIN,JUST AFTER TAKING IN OPERATION THEATRE	TO EVALUATE AND COMPARE EFFICACY OF THREE DIFFERENT DOSES OF INTRANASAL DEXMEDETOMEDINE FOR PREMEDICATION IN CHILDREN FOR PREOPERATIVE ANXIETY USING THE mYPAS SCALEEFFICACY OF THREE DIFFERENT DOSES OF INTRANASAL(ROUTE) DEXMEDETOMEDINE FOR PREMEDICATION IN CHILDREN FOR PREOPERATIVE ANXIETY USING THE mYPAS SCALE TAKING ONE AT BASELINE THEN AFTER ,30MIN,45MIN,JUST AFTER TAKING IN OPERATION THEATRE

Secondary Outcome Measures

Name	Time	Method
1-INDUCTION COMPLIANCE USING INDUCTION COMPLIANCE CHECKLIST.	2-HEMODYNAMIC RESPONSES TO DEFINITIVE AIRWAY INSERTION

Trial Locations

Locations (1)

MAULANA AZAD MEDICAL COLLEGE; 🇮🇳 Delhi, DELHI, India

MAULANA AZAD MEDICAL COLLEGE

🇮🇳Delhi, DELHI, India

NEELAM PRASAD

Principal investigator

9968604372

nprasadgovil@yahoo.com