compare Antimicrobial efficacy of Homeopathic medicines with Ayurvedic and Allopathic medicine against E. faecalis when used as intracanal medicament
- Conditions
- Necrosis of pulp, (2) ICD-10 Condition: R52||Pain, unspecified,
- Registration Number
- CTRI/2021/08/035766
- Lead Sponsor
- SGT Dental college
- Brief Summary
for the Ex Vivo antimicrobial activity of the experimental groups E. Faecalis was grown onto the tooth to form biofilm using BHI broth with the medicament placed in it. The antimicrobial activity was calculated after 7 days using rtPCR technique. for the in vivo study the patient were selected based on inclusion criteria. The Access opening were done and a pre operative sample from the root canal would be taken using paper point. after the completion of cleaning and shaping respective antimicrobial agent would be placed inside the canal as intra canal medicament and the close would be temporarily closed . after a span of 7 days patient would be recalled and second sample would be collected from the canal to check for the antimicrobial activity using rtPCR
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- All
- Target Recruitment
- 100
1.Enough crown structure for adequate isolation, 2.No response to pulp sensibility test, radiographic appearance of periapical radiolucency 3.No history of previous endodontic treatment in the involved tooth.
- Teeth from patients who receive endodontic therapy 2.
- Teeth with gross carious lesions 3.teeth with root or crown fracture 4.patients with marginal periodontitis exhibiting pocket depth deeper than 4mm.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method antimicrobial Activity 7 days
- Secondary Outcome Measures
Name Time Method Pain, swelling 1 week
Trial Locations
- Locations (1)
Himachal Institute of Dental Sciences
🇮🇳Sirmaur, HIMACHAL PRADESH, India
Himachal Institute of Dental Sciences🇮🇳Sirmaur, HIMACHAL PRADESH, IndiaDr Abhiney PuriPrincipal investigator9837633549abhiney72@gmail.com