Vitreous Fragments Length After Pars Plana Vitrectomy
试验速览
- 阶段
- 不适用
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- collagen fragment molecular weigth
研究概览
简要总结
To measure vitreous collagen fragments length after pars plana vitrectomy performed at different cut rates
详细描述
Pars plana vitrectomy consists in the removal of vitreous obtained with a vitreous cutter. The instruments attracts vitreous in its port through active suction and cuts with a blade at different cut rates. There is no consensus as to which cut rate would be ideal in order to minimize traction, neither there is agreement on whether increasing cut rates generate shorter collagen fragments or the fluid turbulence creates unpredictable flows at the port generating fragments of different length.
The investigators plan to gather vitreous cut at 1,000, 2,000, 4,000, 8,000 and 16,000 cuts per minute and measure vitreous collagen average length
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient undergoing pars plana vitrectomy for:
- •macular pucker
- •macular hole-
- •retinal detachment
排除标准
- •unwilling to participate
- •previous trauma
- •vitreous haemorrhage
结局指标
主要结局
collagen fragment molecular weigth
时间窗: at time of surgery
collagen passed through the vitreous cutter is examined with regard to collagen moecular weigth
次要结局
未报告次要终点