Randomised controlled trial comparing the effects of oxytocin 5 units IV bolus vs oxytocin 5 units IV infusion on cardiac output during caesarean section - Effect on cardiac output of oxytocin bolus vs. infusio
Phase 1
- Conditions
- The drug is given routinely to women during caesarean section to help the womb contract after their baby has been delivered. This helps reduce the risk of bleeding after surgery. For this trial, the drug will be given to these women as routine, but the mode of administration will vary between an I.V. bolus or an I.V infusion to assess the effects of administration upon heart rate and blood pressure.MedDRA version: 9.1 Level: LLT Classification code 10006924 Term: Caesarean section
- Registration Number
- EUCTR2007-002949-20-GB
- Lead Sponsor
- iverpool Women's NHS Foundation Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Not specified
- Target Recruitment
- 32
Inclusion Criteria
All patients who are due to undergo elective caesarean section under spinal anaesthesia at more than 37 weeks gestation; ASA grade 1 or 2; age 18 or over.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Conversion to general anaesthetic; placenta praevia; diabetes mellitus; pregnancy induced hypertension; chronic hypertension; patients requiring peri-operative therapeutic anti-coagulant therapy; pre operative anaemia; liver disease; chronic renal failure; history of anaphylaxis to oxytocin.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method