Er:YAG Laser and Air Polishing Application in Periodontal Treatment

Not Applicable

Recruiting

• Conditions: Periodontitis
• Interventions: Procedure: ERL; Procedure: ERL + air polishing

• Registration Number: NCT06574802
• Lead Sponsor: Beijing Chao Yang Hospital

Brief Summary

Periodontitis (gum disease) is an infection of the gums that can lead to tooth loss. In recent years, many types of dental lasers or other devices have been used for the non-surgical treatment of periodontal diseases. However, it remains unclear whether the combined application of laser and air polishing is effective as an adjuvant treatment for periodontitis. The purpose of this study is to compare the use of combined application of Er:YAG laser and sub-gingival air polishing powder, with the treatment of Er:YAG laser only, in periodontal diseases treatment in a Chinese population.

Detailed Description

The study will use a split-mouth design, two quadrants (one quadrant from each jaw) were randomly allocated to either the test or control group. The quadrants in the test group received Er:YAG laser (ERL) plus sub-gingival air polishing treatment, while the quadrants in the control group received ERL only. Clinical periodontal examinations were evaluated at baseline, 3 months, 6 months, 1 year, and 2 years.

Study Timeline

• Status Verified: 2024-08
• Study First Submitted: 2024-08-26
• Study First Submitted QC: 2024-08-26
• Study First Posted: 2024-08-28
• Study Start: 2024-09-04
• Last Update Submitted: 2025-02-05
• Last Update Posted: 2025-02-07
• Primary Completion: 2026-12
• Study Completion: 2027-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• 1. aged 35-65 years old, in good systemic healthy;
• 2. clinically diagnosed with generalized stage Ⅱ or stage Ⅲ periodontitis;
• 3. a minimum of 20 teeth

Exclusion Criteria

• 1. pregnancy or recent pregnancy plans;
• 2. had received periodontal treatment within the previous 6 months;
• 3. taken antibiotics within the previous 3 months;
• 4. had diabetes;
• 5. obvious malocclusion, history of orthodontic treatment, or a habit of mouth breathing.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
control group	ERL	ERL treatment only
test group	ERL + air polishing	Er:YAG laser (ERL) plus sub-gingival air polishing treatment

Primary Outcome Measures

Name	Time	Method
Changes in PD	at 3 months, 6 months, 1 year, and 2 years	Changes in probing depth (PD) measured using periodontal probing
Changes in CAL	at 3 months, 6 months, 1 year, and 2 years	Changes in clinical attachment level (CAL) measured using periodontal probing

Secondary Outcome Measures

Name	Time	Method
changes in BI	at 3 months, 6 months, 1 year, and 2 years	Changes in bleeding index (BI) measured using periodontal probing
PLI	at 3 months, 6 months, 1 year, and 2 years	Plaque index (PLI) assessed by an examiner using a scale of 0 to 3

Trial Locations

Locations (1)

Beijing Chao Yang Hospital; 🇨🇳 Beijing, Beijing, China