A Study to know the effect of Siddha medicine Thiripalathy Legium with Ayakantha Chenduram in treating Iron Deficiency Anaemia

Phase 2

Not yet recruiting

Conditions: Iron deficiency anemia, unspecified,

Registration Number: CTRI/2025/04/085315

Lead Sponsor: National Institute of Siddha

Brief Summary: **BACKGROUND**

Siddha medicine is one of the holistic healing system of medicine in southern India. According to derangement of three humours (Vali, Azhal & Aiyam) diseases are classified as 4448 in number. Paandu Noi is one among them and been classified into 5 types in Yugi Vaidhya Chinthamani.

According to WHO, Anaemia is defined as a condition with haemoglobin level less than 7.7 mmol/l (13g/dl) in men and 7.4 mmol/l (12g/dl) in women which has a wide variety of causes. Iron deficiency is considered to be the most common cause of anaemia.

**PRIMARY OBJECTIVE**

To evaluate the effectiveness of *Siddha* formulation *Thiripalathy Legium* with adjuvant *Ayakantha Chenduram* in the treatment of *Paandu Noi* (Iron Deficiency Anaemia) through haematological investigation of Haemoglobin in Hb gm%, Red Blood Cell Indices and Peripheral Blood Smear before and after treatment.

**SECONDARY OBJECTIVE**

Assessment of improvement through other clinical laboratory blood parameters including Serum Ferritin level and Total Iron Binding Capacity (TIBC).

**TREATMENT PLAN**

Day 1: *Arakku Thailam* is advised for oil Bath.

Day 2: *Agasthiyar Kuzhambu* a gentle laxative is advised.

Day 3: Patient is advised to take rest.

Day 4: *Thiriphalathy legium* will be given as interventional medicine for 90 days.

**INTERVENTIONAL DRUG**

Internal medicine : *THIRIPALATHY LEGIUM*

Dosage : *Arai Thol*a (6g), Twice a day

Adjuvant : Aya kantha Chenduram, 65mg

Duration : Orumandalam (90 days)

**PRIMARY OUTCOME**

Assessment of Haemoglobin level, Red Blood Cell Indices and Peripheral Blood Smear from the baseline and increase in these haematological parameters will be considered as improvement.

**SECONDARY OUTCOME**

The clinical lab parameters including Serum ferritin and Total iron binding capacity will be assessed.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

1.Hb level ranging from seven to nine point nine gram per deciliter According to WHO criteria normal range for adult men is greater than or equal to thirteen gram per deciliter and for adult women is greater than or equal to twelve gram per deciliter 2.Patient willing to undergo blood investigation.

Exclusion Criteria

1.Patient with Renal diseases 2.Patient with Diabetes Mellitus 3.Patient with any malignancy 4.Patient with Tuberculosis 5.Patient with Inherited Blood Disorders 6.Patient with occult blood positive 7.Lactating and pregnant women.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of Haemoglobin level, Red Blood Cell Indices and Peripheral Blood Smear	90 days
from the baseline and increase in these haematological parameters will be considered as improvement.	90 days

Secondary Outcome Measures

Name	Time	Method
The clinical lab parameters including Serum ferritin and Total iron binding capacity will be assessed.	90 days

Trial Locations

Locations (1): Ayothidoss Pandithar Hospital
🇮🇳
Kancheepuram, TAMIL NADU, India
Ayothidoss Pandithar Hospital
🇮🇳Kancheepuram, TAMIL NADU, India
Dr L Lohapriya
Principal investigator
9600159204
drlohapriyalakshmipathy@gmail.com