Etiology, course and long-term effects of Kawasaki disease

Recruiting

• Conditions: Kawasaki disease; mucocutaneous lymph node syndrome; 10011082; 10003216

• Registration Number: NL-OMON50455
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 850

Inclusion Criteria

- Diagnosis of Kawasaki disease according to a standard set of clinical criteria
- Kawasaki disease between the age of 0-18 years
- Inclusion of 300 new cases per 5 years (there are about 100 cases per year in
The Netherlands), which would be 600 cases over the next 10 years.

Exclusion Criteria

None.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. Causative agents: one or more viruses / bacteria involved in triggering<br /><br>Kawasaki disease<br /><br>2. Genetics: genetic variations in the human genome is associated with disease<br /><br>susceptibility, course of the disease (coronary artery aneurysms), and the<br /><br>clinical reaction to standard treatment with IVIG<br /><br>3. Biomarkers: generate novel diagnostic tests<br /><br>4. Long-term effects: assessment of a cardiovascular risk profile</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-</p><br>