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Positioning and the Spontaneous Breathing Test in Neonates

Withdrawn
Conditions
Infants
NICU
Spontaneous Breathing Test
Registration Number
NCT01953562
Lead Sponsor
Christiana Care Health Services
Brief Summary

The spontaneous breathing test (SBT) is routinely performed on all intubated patients in the NICU who are potential candidates for extubation from mechanical ventilatory support. For all parents who consent, the routine SBT will be performed on all infants. In addition to the routine SBT the following will occur:

1. work of breathing indices: obtained non-invasively through respiratory inductive plethysmography (RIP).

2. Performing the SBT in the prone position, in addition to the routine position (supine).

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Infants who qualify for SBT as part of their normal care
Exclusion Criteria
  • Previous history of abdominal or chest surgery (i.e. chest tube, PDA ligation, surgical NEC)
  • Congenital malformation of the chest of abdomen
  • Neuromuscular disorder
  • Current medications affecting neuromuscular tone (ex morphine)
  • Unable to be positioned either prone or supine as determined by the attending neonatologist.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Effect of prone vs supine positioning on whether an infant receives a passing score on the SBT test30 minutes

SBT is a pass/fail test. The effect of prone vs supine positioning in intubated neonates on whether a spontaneous breathing test is scored pass or fail will be determined.

Secondary Outcome Measures
NameTimeMethod
WOB indices during SBT10 minutes

Determination whether prone vs supine position alters the work of breathing indices in infants while receiving a SBT

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