Skip to main content
Clinical Trials/CTRI/2025/08/092151
CTRI/2025/08/092151Not yet recruitingPhase 2/3

Integrated Approach in The Management of Knee Osteoarthritis - A Randomized Control Clinical Trial

KLE Academy of Higher Education and Research1 site in 1 country36 target enrollmentStarted: September 1, 2025Last updated:

Trial Snapshot

Phase
Phase 2/3
Status
Not yet recruiting
Sponsor
Enrollment
36
Locations
1
Primary Endpoint
ESR

Study Overview

Brief Summary

OA is one of the most common joint disorders globally, affecting millions of people. Understanding its causes, progression, and management is essential due to its significant impact on quality of life, healthcare resources, and economic burden. OA is a chronic condition that can lead to chronic pain, disability, and reduced mobility [1]. Sandhigata Vata is the common form of articular disorder. It is most common degenerative joint disease in India.[1] Sandhigat Vata is a type of Vata Vyadhi mainly occurs in Vriddhavastha due to Dhatukshaya, which limits everyday activities such as walking, dressing, bathing etc. [2].

Integrating Ayurveda and homeopathy offers a broader range of treatment options for Sandhivata patients. Each system of medicine brings unique perspectives, diagnostic tools, and therapeutic modalities to the table, allowing for a more comprehensive and holistic approach to patient care.

Both Ayurveda and homeopathy emphasize personalized medicine, taking into account individual constitutional types, symptom profiles, and underlying imbalances. Integrating these systems allows for a more tailored and patient-centered approach to the management of Sandhivata, addressing the specific needs and characteristics of each patient.

Some Ayurvedic herbs and homeopathic remedies may have complementary or synergistic effects when used together. Researching the integration of Ayurvedic and homeopathic interventions for Sandhivata can help identify effective combinations that enhance therapeutic outcomes while minimizing adverse effects.

By studying the integrated approach to Sandhivata, researchers can evaluate the safety and efficacy of combining Ayurvedic and homeopathic treatments. This includes assessing potential herb-drug interactions, dose optimization, and long-term outcomes to ensure the safety and effectiveness of integrative protocols.

Integrating Ayurveda and homeopathy may improve healthcare accessibility by offering patients a wider range of treatment options that align with their cultural beliefs, preferences, and values. This integrative approach promotes patient empowerment and autonomy in healthcare decision-making.

While both Ayurveda and homeopathy have centuries-old traditions, there is a growing interest in generating scientific evidence to support their use in contemporary healthcare settings. Researching the integrated approach to Sandhivata provides an opportunity to contribute to the evidence base for complementary and alternative medicine, helping to bridge the gap between traditional knowledge and modern research methodologies.

In summary, studying the integrated approach to Sandhivata in both Ayurveda and homeopathy offers numerous potential benefits, including expanded treatment options, personalized medicine, synergistic effects, safety and efficacy evaluation, improved healthcare accessibility, and the advancement of research and evidence-based practice in complementary and alternative medicine.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
None

Eligibility Criteria

Ages
40.00 Year(s) to 70.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patients from either sex with classical sign and symptoms of Knee OA Patients of age group 40-70 years.

Exclusion Criteria

  • Patients having major systemic disorders or other illnesses such as Hypothyroidism PCOS Cushing syndrome Hypersensitivity and Diabetes which interfere with the present study.
  • Patients with serious disease limiting life expectancy Pregnancy and lactating mothers Cognitive impairment congenital deformities Not willing to participate in the study.

Outcomes

Primary Outcomes

ESR

Time Frame: Baseline | Day 08 | Day 31

CRP

Time Frame: Baseline | Day 08 | Day 31

Goniometry

Time Frame: Baseline | Day 08 | Day 31

Secondary Outcomes

  • Visual analog pain scale(The Western Ontario and McMaster Universities Osteoarthritis index (WOMAC))

Investigators

Sponsor
KLE Academy of Higher Education and Research
Sponsor Class
Research institution and hospital
Responsible Party
Principal Investigator
Principal Investigator

Dr Suma Rajaput

KAHERs Shri B.M Kankanawadi Ayurveda Mahavidyalaya

Study Sites (1)

Loading locations...

Similar Trials

Study on Combined Ayurvedic and... | Clinical Trial