Creatine in Cognitive Performance (CCP-Study) - in vegetarians and omnivores

Not Applicable

Recruiting

Conditions: healthy subjects

Registration Number: DRKS00017250

Lead Sponsor: niversitätsklinikum Bonn

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 120

Inclusion Criteria

no psychological or physical disorders or disabilities that are likely to cause fluctuations in cognitive performance during the study period
- age is at least 18 years
- eating behaviour is stable, i.e., either omnivore or vegetarian/vegan for at least 6 months
- They have not taken creatine in the last 6 months before the study begins
- They are able to consent
- They do not consume on average more than 20g of alcohol per day (if female) or not more than 40g of alcohol per day (if male)
- They do not consume recreational drugs more than once a week
- They do not do more than 6 hours of intense sports per week

Exclusion Criteria

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Test scores in the two tests:<br>- standardised 10-minute subtest of Raven Advanced Progressive Matrices<br>- Wechsler auditory Backward Digit Span (BDS) task (Wechsler 1955)<br><br>All participants are tested three times: At the beginning, after creatine supplementation and after placebo supplementation. We will test 120 participants. Participation ends for each participant after the third testing round.

Secondary Outcome Measures

Name	Time	Method
We will conduct exploratory analyses for the following measures:<br>D2 Test of Attention (Brickenkamp, 2002)<br>Trail-Making-Test A (TMT-A) (Reitan, 1958)<br>Block-Tapping-Test (BTT) (Schellig, 1997)<br>Auditory Verbal Learning Test (AVLT, in German: VLMT, Helmstaedter & Durwen, 1990)<br>Brief-visuospatial Memory Test –Revised (BVMT-R)<br>Trail-Making-Test B (TMT-B) (Benedict, 1997)<br>Stroop test (Farb-Wort-Interferenz Test, FWI-T, Bäumler, 1985)<br>A test of verbal fluency called Regensburger Wortflüssigkeitstest (RWT)” (Aschenbrenner, Tucha, Lange, 2000)<br>Edinburgh Handedness Inventory (Oldfield, 1971) <br>A test of crystallised intelligence called Mehrfach-Wahl-Wortschatztest (MWT-B)” (Lehrl, 2005)<br>