Comparison of Safety and Efficacy of Drug Eluting Stents : TAXUS (Boston Scientific) vs. LUC-Chopin (Balton, Poland) Implanted Into Saphenous Vein Grafts. Study With Serial Intravascular Ultrasounds.

National Institute of Cardiology, Warsaw, Poland1 site in 1 country50 target enrollmentFebruary 2008

ConditionsStenosis in Saphenous Vein Graft, Drug Eluting Stent

Overview

Phase: Phase 3
Intervention: Not specified
Conditions: Stenosis in Saphenous Vein Graft, Drug Eluting Stent
Sponsor: National Institute of Cardiology, Warsaw, Poland
Enrollment: 50
Locations: 1
Primary Endpoint: Neointima hyperplasia volume by Intravascular Ultrasound
Last Updated: 14 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Drug eluting stents significantly reduced the rate of in-stent restenosis in coronary arteries. There are several kinds of DES i.e. eluting the drug either from stable or biodegradable polymer. The type of the polymer may impact the clinical outcome. The aim of our study was to compare safety and efficacy of implantation of two different types of stents eluting paclitaxel from stable vs biodegradable polymer (TAXUS stent vs LUC-CHOPIN stent) into coronary artery by-pass graft.

Registry

clinicaltrials.gov

Start Date

February 2008

End Date

December 2011

Last Updated

14 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

National Institute of Cardiology, Warsaw, Poland

Eligibility Criteria

Inclusion Criteria

•Atherosclerotic lesion in saphenous vein grafts causing angiographic stenosis ≥70%
•Stable coronary artery disease or non ST segment elevation acute coronary syndrome
•Reference segment diameter in range of 2.5-4.5mm