A study to see the alertness of mind in terms of sleepiness when exposed to white LED or daily using domestic white LED in healthy adults.
Not Applicable
- Registration Number
- CTRI/2022/09/045603
- Lead Sponsor
- Mousumi Ghosh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. age between 18 to 35 years include both male and female
2. literate
3. basic English proficiency
4. regular sleep schedule for 7 to 8 hours where bedtime 10 to 11 pm and wakeup time 6 to 7 am IST
5. global PSQI score less than or equal to 5
6. refractive error with corrected distance VA better than or equal to 20/25 with a healthy retina
Exclusion Criteria
1. any ocular pathology
2. any psychological and neurological disorders, intake of drugs, smoking, alcoholism, intake of caffeine >2 cups/day or >400 mg/day
3. any systemic illness
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method i.Sleep score using Global PSQI scoring (Good sleep indicates PSQI less than 5 and Poor sleep greater than 5) <br/ ><br>ii.Cognitive test using Mini-Cog (quantitative) (Normal: Score 3-5; Cognitive impairment: Score 0-2) <br/ ><br>iii.Pre-frontal cortical responses using ERP (target P300 amplitude in �µV and P300 latency in msec) while performing N-back task when exposed to white LED (in lux). <br/ ><br>iv.Protective efficacy of blue light blocking lenses I, II, and Placebo lens III when exposed to white LED. <br/ ><br>Timepoint: 30 minutes of White LED exposure and 30 minutes of White LED washout using Amber LED.
- Secondary Outcome Measures
Name Time Method i. Protective efficacy of blue light blocking lenses I (Crizal Prevenncia), II (DuraVision BlueProtect), and Placebo lens III (Untinted) when exposed to white LED.Timepoint: 30 minutes of exposure to white LED with each blue-blocking lens.