The relationship between ocular toxicity induced by S-1 and pharmacokinetic analysis in both blood and tear
Not Applicable
- Conditions
- Malignancy
- Registration Number
- JPRN-UMIN000015415
- Lead Sponsor
- Showa University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1) interstitial pneumonia, pulmonary fibrosis 2) Severe active infection 3) Serological positive for HBs-antigen or HCV-antibody 4) Unstable angina or myocardial infarction within 3 months 5) Severe complication (e.g., uncontrollable diabetis mellitus, liver disease) 6) Active synchronous cancer 7) Severe psychiatric disorder 8) Pregnant or lactating women, or men and women without wanting pregnancy 9) Severe hypersensitivity to medicine 10) Patients who were judged inappropriate for the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To identify the pharmacokinetic factors that is associated with ocular toxicity induced by S-1
- Secondary Outcome Measures
Name Time Method