Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT)

Phase 4

Completed

• Conditions: Depression; Suicide, Attempted

• Registration Number: NCT00279682
• Lead Sponsor: Weill Medical College of Cornell University

Brief Summary

The purpose of this study was to determine the effect of a primary care intervention on reducing suicidal ideation and depression in older patients.

Detailed Description

Suicide rates are highest in late life; the majority of older adults who die by suicide have seen a primary care physician in preceding months. Depression is the strongest risk factor for late-life suicide and for suicide's precursor, suicidal ideation.

The aim of the study was to determine the extent to which an intervention taht combined treatment guidelines with care management reduced rates of depression and suicide ideation in older primary care patients. The study randomized 20 primary care practices from New York City, Philadelphia, and Pittsburgh regions into intervention or usual car. The used a two-stage sampling design that resulted in a representative sample with an oversample of depressed patients (total n=1238 subjects including 598 with a depression diagnosis and 640 with no depression diagnosis). Patients were assessed at baseline, 4, 8, 12, 18 and 24 months.

Study Timeline

• Study Start: 1999-05
• Study Completion: 2003-08
• Status Verified: 2006-01
• Study First Submitted: 2006-01-17
• Study First Submitted QC: 2006-01-17
• Last Update Submitted: 2006-01-17
• Study First Posted: 2006-01-19
• Last Update Posted: 2006-01-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1200

Inclusion Criteria

upcoming appointment with primary care clinician

Exclusion Criteria

• inability to give consent
• minimental status examination <18
• ability to communicate in English

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Hamilton Depression Rating Scale
Scale for Suicide Ideation

Secondary Outcome Measures

Name	Time	Method
All cause and cause-specific mortality
disability (Sf12; instrumental activities of daily living)

Trial Locations

Locations (3)

Weill Medical College of Cornell University; 🇺🇸 White Plains, New York, United States

Universilty of Pennsylvania; 🇺🇸 Philadelphia, Pennsylvania, United States

University of Pittsburgh; 🇺🇸 Pittsburgh, Pennsylvania, United States