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临床试验/NCT05395247
NCT05395247招募中不适用

Evaluation gériatrique Avant Transplantation rénale

University Hospital, Caen1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2019年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
500
试验地点
1
主要终点
Inscription on kidney transplantation waiting list

研究概览

简要总结

Geriatric assessment is now widely used to decide whether older patients with chronic kidney disease should be put on the kidney transplantation waiting list. This study aims to evaluate the association between Geriatric assessment and inscription on kidney transplantation.

详细描述

There is a high proportion of older patients among patients with kidney failure, raising the question of the access to kidney transplantation within these patients. Geriatric assessment is now widely used to decide whether older patients with chronic kidney disease should be put on the kidney transplantation waiting list.

This study aims to evaluate the association between Geriatric assessment and inscription on kidney transplantation. Secondary objectives includes the analysis of the association between Geriatric assessment and:

  • post-kidney transplantation outcomes
  • quality of life.

It also includes the evolution of Geriatric assessment while still on waiting list and after kidney transplantation.

This study takes place in an University Hospital in Caen, France. This hospital is the only one performing kidney transplantation in the three French departments around. Candidates for kidney transplantation older than 70 years are systematically evaluated by a trained nurse and a geriatrician to perform a comprehensive geriatric assessment, evaluating cognitive functions, risk of fall, nutrition, frailty, functional status, and depressive symptoms. These patients are followed-up each year while still on the waiting list, and once after kidney transplantation. All patients evaluated within this consultation are proposed to enter the study. Patients are excluded in case of refusal or if they are unable to provide informed consent. The inclusion began in January 2019.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients addressed for Geriatric assessment before inscription on kidney transplantation waiting list in Caen University Hospital, France

排除标准

  • Patient refusal
  • Patient unable to provide informed consent

结局指标

主要结局

Inscription on kidney transplantation waiting list

时间窗: 6 months

Inscription on kidney transplantation waiting list

次要结局

  • Delayed renal recovery following kidney transplantation(1 week after kidney transplantation)
  • Mortality(1 year after kidney transplantation)
  • Length of hospitalization in the year following kidney transplantation(1 year after kidney transplantation)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Cédric VILLAIN

Principal investigator

University Hospital, Caen

研究点 (1)

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