Comparision of Intraoperative Epidural Analgesia and Intraoperative Periarticular Injection on Pain Control After Total Knee Arthroplasty
Phase 4
Completed
- Conditions
- postoperative analgesia after total knee arthroplastyAnaesthesiology - Pain managementSurgery - Other surgery
- Registration Number
- ACTRN12616000226404
- Lead Sponsor
- amik Sahin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 128
Inclusion Criteria
Patients undergoing unilateral total knee arthroplasty as a result of osteoarthritis will be recruited.
Patients will be eligible for inclusion if they are aged greater 18 years, undergoing unilateral total knee arthroplasty as a result of primary osteoarthritis of the knee, can understand and comply with the study protocol,
Exclusion Criteria
- allergy to any drugs used in this study
- previous knee surgery
- bilateral total knee arthroplasty
- severe liver or renal insufficiency
- history of stroke or coronary heart disease
- cognitive impairment
- contraindication for regional anesthesia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method whether epidural morphine or periarticular multimodal drug injection provides better pain control<br><br>The primary outcome is a visual analog scale (VAS) pain score 72 hours after surgery [72 hours post surgery<br>];The primary outcome is a analgesic consumption 72 hours after surgery <br><br><br>Datas of analgesic agent consumption are assessed by review of medical records. Analgesic consumption will be calculated by the total amount of analgesic agents spent on Patient-controlled epidural analgesia (PCEA)<br>[72 hours post surgery ]
- Secondary Outcome Measures
Name Time Method adverse events (itching, allergies, nausea, vomiting, urinary retention, constipation, respiratory depression, bradycardia, hypotension, dizziness i.e.)<br><br>Adverse events were recorded. If adverse events were recognized, They were evaluated according to Common Terminology Criteria for Adverse Events (CTC-AE) ver. 4.0.<br><br>This adverse events listed are assessed as recorded by treating clinician in the medical records<br><br>[72 hours post surgery]