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临床试验/NCT05790577
NCT05790577已完成2 期

Comparison of 30% Metformin and 2% Nicotinamide Lotion With Kligman Formula in the Treatment of Melasma

Ishtiaq Ahmed1 个研究点 分布在 1 个国家目标入组 88 人开始时间: 2022年2月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
2 期
状态
已完成
发起方
入组人数
88
试验地点
1
主要终点
Comparison of 30% Metformin and 2% Nicotinamide lotion with kligman formula in the treatment of Melasma

研究概览

简要总结

Comparison of 30% Metformin and 2% Nicotinamide lotion with kligman formula in the treatment of Melasma

详细描述

A comparative study to evaluate Efficacy and tolerability of new lotion in the treatment of Melasma.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Age between 18-50
  • No systemic therapy
  • All Co-morbids

排除标准

  • Pregnancy
  • Taking oral treatment for melasma

研究组 & 干预措施

Metformin 30% and 2% Nicotinamispde

Active Comparator

Metformin 30% plus Nicotinamide 2% in the reatment of Melasma

干预措施: Metformin and Nicotinamide vs Kligman Formula (Drug)

Kligman formula

Active Comparator

Kligman formula in the treatment of Melasma

干预措施: Metformin and Nicotinamide vs Kligman Formula (Drug)

结局指标

主要结局

Comparison of 30% Metformin and 2% Nicotinamide lotion with kligman formula in the treatment of Melasma

时间窗: 12 weeks

Efficacy with measurement of MASI score 4 weeks apart

次要结局

未报告次要终点

研究者

发起方
Ishtiaq Ahmed
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Ishtiaq Ahmed

Ishtiaq Ahmed

Pak Emirates Military Hospital

研究点 (1)

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