NL-OMON35529
Completed
N/A
Cardiac sympathetic innervation and coronary blood flow regulation during general anesthesia - Coronary blood flow regulation during anesthesia
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- anesthesie
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 65
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age between 18\*75 years
- •Scheduled for non\-cardiac intermediate or high risk surgery
- •Informed consent
- •For patient group 2a: indication for thoracic epidural anesthesia
- •For patient group 2b: undergoing robot assisted thoracic sympathectomy
Exclusion Criteria
- •Known/documented cardiac disease
- •(Untreated) hypertension
- •Abnormal ECG or echocardiogram
- •Peripheral vascular disease
- •Renal disease requiring hemo\- or peritoneal dialysis
- •Inability to perform transthoracic echocardiography
- •Medication interfering with presynaptic catecholamine uptake
- •For patient group 2: contra\-indication for thoracic epidural anesthesia (bleeding diasthesis, infection at the puncture site, patient refusal, severe stenotic valvular disease)
- •Previous allergic reaction to echocardiographic contrast agents
- •Contraindication for use of echocardiographic contrast agent
Outcomes
Primary Outcomes
Not specified
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