Long Term Evaluation of Activity Levels Post Pulmonary Rehabilitation: 1 Year Follow-up
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 65
- 试验地点
- 2
- 主要终点
- Sustained improvement in free-living activities, measured as the average daily METs
研究概览
简要总结
Sustained improvement after pulmonary rehabilitation in activity levels as measured by an activity armband.
Pulmonary rehabilitation is utilized to improve exercise capacity, quality of life and prognosis for patients who suffer from chronic obstructive pulmonary disease. There is also strong evidence that supports the use of pulmonary rehabilitation to decrease hospital admissions thereby reducing cost of care. Recent studies suggest that the significant benefits achieved through rehabilitation fade with time and that in order to improve activities of daily living; for example, average daily number of steps, programmes of longer duration are required.
The primary aim of this study is to identify objective sustained improved in activity levels using the SenseWear activity armband after a short-term pulmonary rehabilitation programme. Secondary aims are to determine antibiotic and steroid use pre and post rehabilitation.
详细描述
Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and by both systemic and airway inflammation. Together these features lead to decreased physical activity which in turn worsens the patient's dyspnoea. In patients with COPD, physical activity levels are low compared to healthy controls and indeed lower than in patients with other chronic conditions such as arthritis and diabetes. For patients with COPD, decreased physical activity and breathlessness are significant predictors of mortality and morbidity. By reversing deconditioning pulmonary rehabilitation using supervised and home exercise programs leads to increased exercise capacity and health quality of life scores. In order for the benefits of pulmonary rehabilitation to be sustained in the long-term it is essential that there is a change in the patient's physical activity in their home life. While practice guidelines recommend that there is transference of exercise to the home setting it is unknown if this happens in reality. Addressing whether there is an increase in physical activity at home after pulmonary rehabilitation is the focus of this study.
Physical activity can be measured in a number of ways, including direct observation, patient diaries and questionnaires, but one of the most successful are the performance based motion sensors such as pedometers and accelerometers. One such performance based motion sensor is the SenseWear accelerometer. The SenseWear has previously been used in patients with COPD, has been shown to be a reliable measure of physical activity performed in this population, other than those using rolators and it is objectively more accurate than questionnaires and diaries. The hypothesis of this study was that pulmonary rehabilitation leads to a sustained improvement in physical activity in patients with COPD. Physical activity was measured by the daily averaged activity recorded with a SenseWear armband at several time points in the year after a course of pulmonary rehabilitation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 35 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A diagnosis of COPD based on the GOLD staging of the disease
- •Referred to pulmonary rehabilitation by a respiratory consultant or member of the COPD Team
- •Modified Medical Research Council Score of 3 or above
- •Ability to mobilize independently
- •Motivated to exercise independently
排除标准
- •No evidence of COPD on spirometry
- •Acute exacerbation within the last 4-6 weeks
- •Evidence of ischemic heart disease/acute changes on ECG
- •Uncontrolled hypertension
- •Insulin dependent diabetes mellitus
- •Inability to exercise independently or musculoskeletal/neurological conditions which would prevent completion of the course
- •Lung cancer previous attendance at pulmonary rehabilitation
结局指标
主要结局
Sustained improvement in free-living activities, measured as the average daily METs
时间窗: At the end of 1 year compared to baseline
Using an accelerometer, which will be worn by patients for seven consecutive days at each time frame, daily average measurements of the number of steps per day, total energy expenditure and METs that will be broken down into sedentary, moderate and vigorous, plus sleep time and efficiency.
次要结局
- Quality of Life(baseline will be compared to that at 1 year follow-up)
- The Incremental Shuttle Walk Test(baseline will be compared to that at 1 year follow-up)
- The Modified Medical Research Council Scale(baseline will be compared to that at 1 year follow-up)
- Pulmonary Function Tests(baseline will be compared to that at 1 year follow-up)
- Borg Score(baseline will be compared to that at 1 year follow-up)
研究者
Professor Richard Costello
Professor of Medicine
Beaumont Hospital