Role of Magnetic Resonance Imaging in Evaluation of Uterine Cesarean Section Scar Niche
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 主要终点
- MRI pelvis examination (sagittal T2WI ) using 1.5 tesla system Torso phased-array body coil with the patient in the supine position and a moderately full urinary bladder
研究概览
简要总结
To evaluate cesarean section scar and the lower uterine segment in non pregnant woman by MRI to :
- Assess the clinical symptoms like postmenstrual spotting or prolonged menstrual bleeding, dysmenorrhea, chronic pelvic pain and dyspareunia and its relation to the presence of cesarean scar defects and its characteristics .
- development of scoring system and correlating it with the symptoms .
详细描述
With increasing cesarean section rate nowadays, the risks of cesarean scar defect (CSD) should increase. CSD is defined by ultrasound imaging as a triangular hypoechoic defect in the myometrium at the site of the previous cesarean section scar. However, patients with CSD are sometimes asymptomatic. Yet, some patients with CSD can have symptoms of abnormal uterine bleeding, pelvic pain, infertility, uterine rupture, and potential risks of adverse pregnancy outcome .There is an association between the size of a niche and postmenstrual spotting. women with a history of CS, the depth and shape of the niche were not significant factors, while a larger niche volume was described in women with postmenstrual spotting. in women with gynecological symptoms, the niches were significantly wider in women with postmenstrual spotting, dysmenorrhea or chronic pelvic pain, and the prevalence of postmenstrual spotting or prolonged menstrual bleeding was higher with a larger diameter of the niche .Magnetic resonance imaging (MRI) has recently shown a promise tool for evaluation of uterine scar thickness. As opposed to ultrasonography (USG), which is the current gold standard for this purpose, MRI reduces observer dependence and has a superior multiplanar capability.
MRI can be used for assessment of lower uterine segment. It provides accurate tissue characterization, independent of patient body mass index .
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •previous lower uterine segment cesarean section before .
- •At least 6 months after the last cesarean section .
- •still regularly menstruating .
- •Absence of other gynecological disease or intrauterine lesions like endometriosis , uterine fibroid .
排除标准
- •Post menopausal women .
- •hysterectomy .
- •Presence of other gynecological disease like endometriosis , uterine fibroids .
- •any general contraindication to MRI as presence of any paramagnetic substance as pacemakers or in severely ill patients or those with claustrophobia, arrhythmic patients .
- •intrauterine devices .
- •bleeding tendency.
结局指标
主要结局
MRI pelvis examination (sagittal T2WI ) using 1.5 tesla system Torso phased-array body coil with the patient in the supine position and a moderately full urinary bladder
时间窗: baseline
Scar shape were classified as "U" shape, "V" shape and mixed shape, judging from the transitional region from scar to normal uterine or cervical wal
次要结局
- transabdominal and transvaginal ultrasound examination(baseline)
- clinical evaluation(baseline)
研究者
Kero Wagdy
resident doctor
Assiut University
